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Jean-Louis Lefaix Selected Research

pentoxifylline-tocopherol-clodronate

7/2011Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a phase II trial.
12/2008Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo).

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Jean-Louis Lefaix Research Topics

Disease

4Radiation Fibrosis Syndrome (Radiation Fibrosis)
12/2012 - 07/2003
4Fibrosis (Cirrhosis)
12/2008 - 06/2002
3Neoplasms (Cancer)
08/2015 - 01/2015
3Osteoradionecrosis
07/2011 - 11/2004
2Chondrosarcoma
08/2015 - 02/2015
2Peripheral Nervous System Diseases (PNS Diseases)
12/2012 - 12/2008
2Necrosis
12/2008 - 04/2007
1Sarcoma (Soft Tissue Sarcoma)
08/2015
1Uveal melanoma
05/2015
1Rupture
02/2015
1Hypoxia (Hypoxemia)
01/2015
1Seminoma
12/2012
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
12/2012
1Hodgkin Disease (Hodgkin's Disease)
12/2012
1Head and Neck Neoplasms (Head and Neck Cancer)
07/2011
1Closed Fractures (Closed Fracture)
07/2011
1Polyradiculopathy
12/2008
1Inflammation (Inflammations)
04/2007
1Cicatrix (Scar)
06/2002

Drug/Important Bio-Agent (IBA)

6Pentoxifylline (Trental)FDA LinkGeneric
07/2011 - 07/2003
5Tocopherols (Tocopherol)IBA
12/2008 - 07/2003
2IonsIBA
08/2015 - 05/2015
2CarbonIBA
08/2015 - 05/2015
2Oxygen (Dioxygen)IBA
08/2015 - 07/2011
2AntioxidantsIBA
12/2012 - 12/2008
2pentoxifylline-tocopherol-clodronateIBA
07/2011 - 12/2008
1CollagenIBA
08/2015
1Messenger RNA (mRNA)IBA
01/2015
1Vitamin EFDA LinkGeneric
07/2011
1Carisoprodol (Soma)FDA LinkGeneric
07/2011
1Analgesics (Analgesic Drugs)IBA
07/2011
1Clodronic Acid (Clodronate)IBA
12/2008
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2007
1SteroidsIBA
04/2007
1alpha-TocopherolFDA Link
12/2005
1Proliferating Cell Nuclear Antigen (PCNA)IBA
06/2002

Therapy/Procedure

6Radiotherapy
02/2015 - 06/2002
2Aftercare (After-Treatment)
12/2005 - 02/2005
1Therapeutics
08/2015
1Conformal Radiotherapy
12/2012